Article Text
Abstract
Autoimmune hepatitis (AIH) is an autoimmune liver disease characterised by the presence of autoantibodies including antinuclear antibodies, anti-smooth muscle antibody and hypergammaglobulinaemia. Systemic lupus erythematosus (SLE) is a systemic disease that can affect multiple organs. Coexistence of AIH and SLE as an overlap syndrome occurs in about 1%–2.6% of the AIH cases. Since both conditions share common autoimmune features, their coexistence can pose a diagnostic dilemma which can result in a delay in treatment. We present here a challenging case of a middle-aged woman with AIH in remission who later developed new-onset fatigue, pleural effusion and splenomegaly.
- liver disease
- rheumatology
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Footnotes
Twitter @dgoyesv, @vijayramreddym, @hepatology
DG and VRM contributed equally.
Contributors DG, VM, RI and AA-K—planning. DG, VM, RI and AA-K—conduct. DG, VM, RI and AA-K—reporting. DG, VM, RI and AA-K—conception and design. DG, VM, RI and AA-K—writing (review and editing).
Funding The authors have not declared a specific grant for this research from any funding agency in the public, commercial or not-for-profit sectors.
Competing interests None declared.
Patient consent for publication Obtained.
Provenance and peer review Not commissioned; externally peer reviewed.