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Simultaneous surgical management of unilateral limbal stem cell deficiency and symblepharon post chemical burn
  1. Swapna S Shanbhag1,
  2. Shilpa Tarini1,
  3. Anuradha Kunapuli1 and
  4. Sayan Basu1,2
  1. 1The Cornea Institute, LV Prasad Eye Institute, Hyderabad, Telangana, India
  2. 2Brien Holden Eye Research Centre (BHERC), LV Prasad Eye Institute, Hyderabad, Telangana, India
  1. Correspondence to Dr Sayan Basu; sayanbasu{at}


A 6-year-old female child presented with severe acute ocular chemical burn in the right eye 2 days after injury with cement. She underwent removal of all foreign bodies from the ocular surface and amniotic membrane transplantation. Three months later, she developed unilateral total limbal stem cell deficiency (LSCD) with symblepharon in two quadrants. Three months after the acute injury, the patient underwent autologous simple limbal epithelial transplant in the right eye with one-clock hour of limbus harvested from the left eye. At the same sitting, she underwent symblepharon release in two quadrants of the right eye with conjunctival autograft harvested from the left eye followed by conjunctival graft suturing to the areas of bare sclera in the right eye. One year after surgery, the patient’s visual acuity improved from counting fingers close to face preoperatively to 20/50 (uncorrected) with no recurrence of LSCD or symblepharon.

  • anterior chamber
  • paediatric surgery
  • transplantation

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  • Contributors SS and SB clinically managed the case. SS, ST and AK performed acquisition of data, analysis and interpretation of data, a literature review and drafted the manuscript. All four authors approved the final version of the manuscript.

  • Funding This study was funded by Hyderabad Eye Research Foundation.

  • Competing interests None declared.

  • Patient consent for publication Parental/guardian consent obtained.

  • Provenance and peer review Not commissioned; externally peer reviewed.

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