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Silent and formidable foe: neuroendocrine tumours of the gallbladder
  1. Darshan S Randhawa,
  2. Sami Shoucair and
  3. Edward McCarron
  1. Department of Surgery, MedStar Health, Columbia, Maryland, USA
  1. Correspondence to Dr Darshan S Randhawa; darshan.s.randhawa{at}


Neuroendocrine neoplasms of the gallbladder occur infrequently, with the diagnosis being incidental in most cases. We present a case of an 81-year-old African American woman who initially presented with acute suppurative cholecystitis, found on pathology to have a moderately differentiated infiltrating adenocarcinoma. A partial hepatic resection with periportal lymph node dissection was planned which was subsequently aborted intraoperatively due to the presence of diffuse carcinomatosis. Pathology of the cancerous lesions revealed neuroendocrine carcinoma. Gallbladder neuroendocrine tumours demonstrate no specific clinical features. Given its often late presentation, neuroendocrine tumours of the gallbladder pose a therapeutic and prognostic challenge.

  • biliary intervention
  • endocrinology
  • medical management
  • endocrine cancer
  • general surgery

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  • Contributors DSR: conception or design of the work, data collection, data analysis and interpretation, drafting the article and critical revision of the article. SS: drafting the article. EM: drafting the article and critical revision of the article.

  • Funding The authors have not declared a specific grant for this research from any funding agency in the public, commercial or not-for-profit sectors.

  • Competing interests None declared.

  • Patient consent for publication Not required.

  • Provenance and peer review Not commissioned; externally peer reviewed.

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