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Delayed urticaria or anaphylaxis after consumption of red meat with evidence of alpha-gal sensitisation
  1. Maria Beatriz Garcia1,2,3,
  2. Andres F Gomez-Samper3,
  3. Elizabeth Garcia1,2,3 and
  4. Augusto Peñaranda3,4,5
  1. 1Allergology Service, Fundacion Santa Fé de Bogotá, Bogotá, Colombia
  2. 2Allergology Service, Unimeq, Bogotá, Colombia
  3. 3School of Medicine, Universidad de los Andes, Bogotá, Colombia
  4. 4Otolaryngology Department, Fundación Santa Fé de Bogotá, Bogotá, Colombia
  5. 5Otolaryngology Service, Unimeq, Bogotá, Colombia
  1. Correspondence to Ms Maria Beatriz Garcia; marabagarcia{at}


Food allergies to red meat, specifically to galactose-alpha-1,3-galactose (alpha-gal), a mammalian oligosaccharide, are considered to be very rare, especially in Asia and Latin America. Most of the cases reported are characterised by symptoms of delayed urticaria or anaphylaxis after the consumption of red meat. Sensitisation to red meat has been linked to the use of cetuximab or tick bites, especially from the Amblyomma americanum and Ixodes spp species. Here, we documented a case study from a Colombian male patient with symptoms of delayed urticaria and anaphylaxis with a history of tick bites in Colombia. The patient presented with IgE antibodies specific to alpha-gal, which is the most common epitope linked to red meat allergy induced by tick bites.

  • dermatology
  • immunology

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  • Contributors MBG: evaluation, diagnosis and treatment of the patient. Description of the patient’s medical history. AFG-S: writing paper, analysis of the case, association with the literature described on the subject. AP: supervision of the clinical case study from the diagnosis of the patient to the writing of the paper. Form and writing review. EG: supervision of the clinical case study from the diagnosis of the patient to the writing of the paper. Form and writing review.

  • Funding The authors have not declared a specific grant for this research from any funding agency in the public, commercial or not-for-profit sectors.

  • Competing interests None declared.

  • Patient consent for publication Obtained.

  • Provenance and peer review Not commissioned; externally peer reviewed.