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Unilateral persistent disc oedema due to cerebral sinus venous thrombosis (CSVT): diagnostic and management challenge
  1. Rohan Nalawade1,
  2. Mohan Kannam1,
  3. Butchi Raju Garuda2 and
  4. Virender Sachdeva3
  1. 1Fellow Academy of Eye Care Education, Child Sight Institute, Nimmagadda Prasad Children’s Eye Care Centre, LV Prasad Eye Institute, GMR Varalakshmi Campus, Visakhapatnam, India
  2. 2Department of Neurology, Andhra Medical College, Visakhapatnam, Andhra Pradesh, India
  3. 3Consultant, Department of Pediatric Ophthalmology, Strabismus and Neuro-Ophthalmology, Child Sight Institute, Nimmagadda Prasad Children’s Eye Care Centre, LV Prasad Eye Institute GMR Varalakshmi Campus, Visakhapatnam, India
  1. Correspondence to Dr Virender Sachdeva; drvsachdeva29{at}


A 50-year-old woman was incidentally diagnosed to have unilateral disc oedema during comprehensive ophthalmological evaluation. She had a prior history of ulcerative colitis. She had normal visual function and was initially diagnosed to have incipient non-arteritic anterior ischaemic optic neuropahty. Risk factor evaluation revealed hyperhomocysteinaemia. She was asked to come for a follow-up in 2 months. However, she was lost to follow-up and returned to the clinic for the evaluation for headaches, 23 months later. Her ocular examination was stable and she had persistent unilateral disc oedema unchanged from the prior visit. Repeat MRI brain and MR venogram brain with contrast-established diagnosis of cerebral sinus venous thrombosis (CSVT). She denied any neurological symptoms. Later on, she was diagnosed to have hyperhomocysteinaemia with methyl tetrahydrofolate reductase gene mutation. This case highlights the importance of recognising although rare, unilateral disc oedema secondary to elevated intracranial pressure from CSVT.

  • neuroopthalmology
  • neuroimaging

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  • Contributors VS contributed in concept and design. RN, MK and VS contributed in manuscript preparation and collection of data. RN, MK, BRG (Butchi Raju Garuda) and VS contributed in critical revision of the manuscript.

  • Competing interests None declared.

  • Patient consent for publication Obtained.

  • Provenance and peer review Not commissioned; externally peer reviewed.