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Acute nephrotoxicity and neurotoxicity associated with concentrated star fruit juice consumption
  1. Isolda Prado de Negreiros Nogueira Maduro1,2,
  2. Alba Regina Jorge Brandão3 and
  3. Karla Cristina Petruccelli Israel3
  1. 1Department of Clinical Nutrition, Universidade do Estado do Amazonas Escola Superior de Ciencias da Saude, Manaus, Brazil
  2. 2Department of Internal Medicine, Fundação Hospital Adriano Jorge, Manaus, Amazonas, Brazil
  3. 3Department of Nephrology, Centro de Doenças Renais do Estado do Amazonas, Manaus, Amazonas, Brazil
  1. Correspondence to Dr Isolda Prado de Negreiros Nogueira Maduro; isoldaprado{at}


Star fruit toxicity has been hugely described in patients with chronic kidney disease, either on conservative or renal replacement therapy. This is a case report of a man, without prior kidney or neurological dysfunction, who appeared to develop nephrotoxicity and neurotoxicity less than 12 hours after drinking concentrated star fruit juice (approximately 20 units of the fruit). He received timely renal replacement therapy and renal function fully recovered after discharge.

  • acute renal failure
  • dialysis
  • neurological injury
  • adult intensive care
  • nutrition

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  • Contributors Substantial contributions to the conception or design of the work were made by IPdNNM. Data acquisition, as well as analysis and interpretation and intellectual content were authored by ARJB. Writing, data acquisition, work review was written by KCPI.

  • Funding The authors have not declared a specific grant for this research from any funding agency in the public, commercial or not-for-profit sectors.

  • Competing interests None declared.

  • Patient consent for publication Obtained.

  • Provenance and peer review Not commissioned; externally peer reviewed.

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