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Haemorrhagic nasal polyp mimicking melanoma in an 83-year-old on rivaroxaban
  1. Alison Liu,
  2. Sean Fang,
  3. Karan Kapoor and
  4. Humera Babar-Craig
  1. ENT, Surrey and Sussex Healthcare NHS Trust, Redhill, UK
  1. Correspondence to Alison Liu; alison.liu{at}


An 83-year-old woman presented with rapid onset unilateral nasal obstruction after sneezing. She had a history of hypertension and atrial fibrillation, and was on rivaroxaban. Examination revealed a dark red polypoidal lesion completely obstructing the left nostril. She underwent CT and MRI, and proceeded to urgent excision biopsy of the lesion. Intraoperative appearance was in keeping with a haemorrhagic polyp arising from the nasal septum. Histology revealed haematoma within a layer of nasal mucosa. There was no evidence of haemangioma underlying the polyp. Our literature search has identified this case as the first described haemorrhagic polyp of the nasal septum. It is likely that rivaroxaban contributed to the formation of this haemorrhagic polyp, and it is important to differentiate benign haemorrhagic lesions from malignant conditions such as melanoma. Similar cases may become more common in the future as the proportion of the population on anticoagulants increases.

  • ear
  • nose and throat/otolaryngology
  • nasal polyps
  • pharmacology and therapeutics
  • otolaryngology / ENT
  • head and neck cancer

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  • Contributors AL wrote the body of this case. SF reviewed and edited the case and advised on clinical guidelines for management of sinonasal lesions. KK initially saw the patient and referred them to HB-C. HB-C was the supervising consultant and provided the clinical details and consent for this case.

  • Funding The authors have not declared a specific grant for this research from any funding agency in the public, commercial or not-for-profit sectors.

  • Competing interests None declared.

  • Patient consent for publication Obtained.

  • Provenance and peer review Not commissioned; externally peer reviewed.