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Colon metastases as first clinical manifestation of lobular breast carcinoma with no subsequent evidence of breast disease
  1. Mohammed Isaac Abu Zaanona1,
  2. Aishwarya Gulati1,2 and
  3. Kendrith Rowland3
  1. 1Internal Medicine, Carle Foundation Hospital, Urbana, Illinois, USA
  2. 2Radiology, Thomas Jefferson University Hospital, Philadelphia, Pennsylvania, USA
  3. 3Oncology, Carle Foundation Hospital, Urbana, Illinois, USA
  1. Correspondence to Dr Mohammed Isaac Abu Zaanona; mabuzaanona{at}


A 73-year-old woman was brought to the oestrogen receptor for altered mental status. She was found to be hypotensive and hypoglycaemic and admitted to the intensive care unit. She had a history of chronic watery diarrhoea which had recently increased over the last 2 weeks and was associated with vague abdominal pain. A CT showed bowel wall thickening concerning for colitis. Due to the increasing diarrhoea, a colonoscopy was done after all stool studies came back negative. Polyps in the ascending, transverse and sigmoid colon were found to be tubular adenomas but random colonic mucosa biopsies were revealed to be histologically consistent with metastatic lobular breast carcinoma. Further workup revealed no primary breast disease.

  • breast cancer
  • colon cancer

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  • Contributors MIAZ and AG were involved in the data acquisition, and interpretation, and drafting of the manuscript. KR was involved in patient care, supervision of data acquisition, interpretation and drafting of the manuscript. MIAZ and AG are joint first authors of this case report.

  • Funding The authors have not declared a specific grant for this research from any funding agency in the public, commercial or not-for-profit sectors.

  • Competing interests None declared.

  • Patient consent for publication Obtained.

  • Provenance and peer review Not commissioned; externally peer reviewed.

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