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Case report
Spontaneous extrusion of a dexamethasone intravitreal implant (Ozurdex)
  1. Jessica Ong1,
  2. Nishant Hemanth Davidoss1,
  3. Anant Bhosale1,2 and
  4. Chandrakumar Balaratnasingam1,3
  1. 1Ophthalmology, Sir Charles Gairdner Hospital, Nedlands, Western Australia, Australia
  2. 2Retina and Vitreous, Aravind Eye Hospital Coimbatore, Coimbatore, India
  3. 3Lions Eye Institute, Nedlands, Western Australia, Australia
  1. Correspondence to Dr Jessica Ong; jessong919{at}


A 59-year-old man with diabetic macular oedema was treated with a dexamethasone intravitreal implant (Ozurdex) to his right eye. Immediately after injection, the implant was noted to have extruded into the perilimbal subconjunctival space. The remnants of the implant were expeditiously removed the following day to avoid corneal decompensation and permanent corneal oedema. Endothelial decompensation secondary to the migration of dexamethasone implants into the subconjunctival space or anterior chamber is a recognised complication of Ozurdex injection. The patient recovered well postoperatively with no further complications. He was planned for a new Ozurdex implant 1 month later.

  • anterior chamber
  • retina
  • eye

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  • Contributors AB, NHD and JO contributed to the conception and design of this work. JO wrote the original manuscript draft and is the primary author. NHD and AB provided revisions to the content of the manuscript. AB provided the images used in this report. All authors contributed to the final approval of the manuscript.

  • Funding The authors have not declared a specific grant for this research from any funding agency in the public, commercial or not-for-profit sectors.

  • Competing interests None declared.

  • Patient consent for publication Obtained.

  • Provenance and peer review Not commissioned; externally peer reviewed.