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Case report
Rare complication of COVID-19 presenting as isolated headache
  1. Rehan Asif1 and
  2. Marcella Sinead O' Mahony2
  1. 1Rheumatology & GIM, University Hospital of Wales, Cardiff, UK
  2. 2Geriatric Medicine, University Hospital Llandough, Llandough, South Glamorgan, UK
  1. Correspondence to Dr Rehan Asif; rehanasifqmc{at}


An 18-year-old man presented with persistent isolated headache 2 weeks after recovering from acute COVID-19 illness. Extensive cerebral venous sinus thrombosis (CVST) was detected on CT venogram despite him having no other thrombotic risk factors. CVST can complicate COVID-19. A high index of clinical suspicion is warranted as it can often have a subtle presentation with paucity of neurological symptoms.

  • venous thromboembolism
  • headache (including migraines)
  • infectious diseases

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  • Contributors RA was involved in the planning, literature search design and writing of the case report. MSOM was the consultant in change of this patient and provided oversight of the article, proof reading and review of the article.

  • Funding The authors have not declared a specific grant for this research from any funding agency in the public, commercial or not-for-profit sectors.

  • Competing interests None declared.

  • Patient consent for publication Obtained.

  • Provenance and peer review Not commissioned; externally peer reviewed.