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Case report
Oesophageal GIST
  1. Filipa Costa1,
  2. Rui Casaca2,
  3. Cecilia Monteiro2 and
  4. Paulo Ramos2
  1. 1Hospital Sao Francisco Xavier, Lisboa, Portugal
  2. 2Instituto Portugues de Oncologia de Lisboa Francisco Gentil EPE, Lisboa, Portugal
  1. Correspondence to Dr Filipa Costa; filipacc{at}


Gastrointestinal stromal tumours (GISTs) are the most common mesenchymal tumours of the gastrointestinal tract. Oesophageal GISTs are extremely uncommon, accounting for 0.7% of all GISTs, and their management is surrounded by some debate. We report a case of a 70-year-old man who was incidentally diagnosed with an oesophageal lesion on a 18F-fluorodeoxyglucose positron emission tomography. An endoscopic study revealed a non-obstructing 40 mm oesophageal lesion. Endoscopic ultrasound showed a well-circumscribed submucosal tumour on the middle oesophagus. Fine-needle aspiration was positive for CD117 and the overall features were of a GIST. After an initial thoracoscopic approach, the tumour was completely enucleated through a thoracotomy incision. The patient experienced no surgical complications and was discharged on day 4. Histopathology and immunohistochemical staining confirmed a low-risk GIST.

  • oesophageal cancer
  • general surgery
  • cardiothoracic surgery
  • surgical oncology
  • cancer intervention

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  • Contributors All the authors were involved on the clinical case, during surgery and patient follow up. All were responsible for conception of the work. FC and RC were involved in planning and supervised the work. FC were responsible for drafting the article and took the lead in writing the manuscript. CM and PR did a critical revision and editing. RC discussed the results and provided critical feedback.

  • Funding The authors have not declared a specific grant for this research from any funding agency in the public, commercial or not-for-profit sectors.

  • Competing interests None declared.

  • Patient consent for publication Obtained.

  • Provenance and peer review Not commissioned; externally peer reviewed.