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Case report
Maternal complications of fetal triploidy: a case report
  1. Sarah Wali1 and
  2. Marianne Wild2
  1. 1Department of Obstetrics and Gynaecology, Imperial College Healthcare NHS Trust, London, UK
  2. 2Department of Obstetrics & Gynaecology, Homerton University Hospital NHS Foundation Trust, London, UK
  1. Correspondence to Dr Sarah Wali; sarah.wali{at}


A 32-year-old woman underwent a medical termination in the second trimester of a spontaneously conceived triploid pregnancy after developing early-onset preeclampsia with subsequent haemolysis, elevated liver enzymes, and low platelet count (HELLP) syndrome. Placental histology was normal (non-molar) and unusually, she developed ovarian hyperstimulation syndrome (OHSS) 4 weeks later. She was managed conservatively following multidisciplinary team input to exclude malignant pathology. The rarity of late-onset spontaneous OHSS could have resulted in inappropriate surgical management. In the absence of supportive treatment there is also a risk of the condition progressing to a critical stage. Follow-up ultrasonography after termination of pregnancy should be considered for women with evidence of ovarian hyperstimulation, particularly if other risk factors for OHSS are present. Delayed-onset OHSS should be considered in women presenting with bilateral cystic ovarian enlargement after triploid pregnancy.

  • obstetrics and gynaecology
  • abortion
  • pregnancy
  • ultrasonography

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  • Contributors Both SW and MW contributed to the drafting and revision of the manuscript and approved the final version for submission.

  • Funding The authors have not declared a specific grant for this research from any funding agency in the public, commercial or not-for-profit sectors.

  • Competing interests None declared.

  • Patient consent for publication Obtained.

  • Provenance and peer review Not commissioned; externally peer-reviewed.