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Clear cell chondrosarcoma of proximal femur: a rare entity with diagnostic dilemma
  1. Manish Pruthi1,
  2. Jagandeep Singh Virk2,
  3. Anila Sharma3 and
  4. Vivek Mahawar4
  1. 1Musculoskeletal Oncology, Rajiv Gandhi Cancer Institute and Research Centre, New Delhi, Delhi, India
  2. 2Orthopaedic Oncosurgery, Paras Hospitals, Gurgaon, Haryana, India
  3. 3Histopathology, Rajiv Gandhi Cancer Institute and Research Centre, New Delhi, Delhi, India
  4. 4Radiology, Rajiv Gandhi Cancer Institute and Research Centre, New Delhi, Delhi, India
  1. Correspondence to Dr Jagandeep Singh Virk; jaganvirk_09{at}


Clear cell chondrosarcoma is an extremely rare malignant neoplasm. The rarity and slow-growing nature of this tumour often lead to prolonged symptoms and also initial misdiagnosis with benign lesions such as chondroblastoma. It can also be confused with avascular necrosis of the femoral head when the lesion is located in the femoral head, as was in the case we report. The patient was kept on observation and conservative treatment for almost 9 years before the correct diagnosis and appropriate treatment. Wide local resection with negative margins forms the mainstay of treatment since intralesional procedures predispose to high local recurrence rate. A prolonged follow-up is recommended since late local recurrences and metastases are common.

  • musculoskeletal and joint disorders
  • surgical oncology

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  • Contributors MP did the conception and final approval. JSV interpreted the data, designed and structured the report, and conducted acquisition and interpretation of data. AS carried out the pathological review and diagnosis, and VM conducted the radiological diagnosis.

  • Funding The authors have not declared a specific grant for this research from any funding agency in the public, commercial or not-for-profit sectors.

  • Competing interests None declared.

  • Patient consent for publication Obtained.

  • Provenance and peer review Not commissioned; externally peer-reviewed.