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Case report
Pancreatic mesothelial cyst
  1. Charbel Chater1,2,
  2. Joseph Obeid Obeid1,2 and
  3. Seba Mhanna1,2
  1. 1Department of General Surgery, Notre Dame des Secours University Hospital Center, Jbeil, Mont-Liban, Lebanon
  2. 2Holy Spirit University of Kaslik Faculty of Medicine and Medical Sciences, Jounieh, Lebanon
  1. Correspondence to Dr Charbel Chater; charbeliban{at}


A 60-year-old woman was investigated for abdominal pain and increasing asthenia. Abdominal CT revealed a 25 mm hypodense cystic lesion in the tail of the pancreas. MRI showed a multiloculated cystic lesion, T1-hypointense and T2-hyperintense lesion, without wall enhancement. Endoscopic ultrasound detected a 25 mm multi-loculated cystic lesion, with regular margin and without pancreatic duct communication. Diagnosis of pancreatic mucinous cystadenoma was discussed and the patient was referred to surgery. She underwent distal pancreatectomy with spleen preservation. Pathological examination revealed the diagnosis of pancreatic mesothelial cyst. Histologically, the cyst was multiloculated, lined by cuboidal epithelium, ovoid nuclei and amphophilic cytoplasm, without mucin deposition or cytological atypia. Immunohistochemistry examination revealed positive staining for cytokeratin 5/6, vimentin and calretinin. At 1-year follow-up, she is in her usual health, without any symptoms.

  • gastrointestinal surgery
  • general surgery
  • pancreas and biliary tract

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  • Contributors CC, JOO and SM have been involved in the patient’s care. All authors have made an individual contribution to the writing of the article: CC contributed to the conception, design, acquisition of data, analysis and drafting this manuscript. JOO contributed to the conception, acquisition of data, revising the article with critical feedback and writing the final manuscript. SM contributed to the conception, design, analysis of data, revising the article with critical feedback and writing the final manuscript. CC wrote the manuscript. JOO and SM provided critical feedback. CC, JOO and SM contributed to the final manuscript. CC, JOO and SM have contributed to the final version and have approved the submission.

  • Funding The authors have not declared a specific grant for this research from any funding agency in the public, commercial or not-for-profit sectors.

  • Competing interests None declared.

  • Patient consent for publication Obtained.

  • Provenance and peer review Not commissioned; externally peer reviewed.