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Case report
The snoring 2-year-old boy: a case of primary nasopharyngeal Burkitt’s lymphoma
  1. Gerd Xuereb1,2,
  2. Justine Borg2,
  3. Kurt Apap2,3 and
  4. Charles Borg2,4
  1. 1Foundation Programme Malta, Mater Dei Hospital, Msida, Malta
  2. 2Faculty of Medicine & Surgery, University of Malta, Msida, Malta
  3. 3Emergency Department, Mater Dei Hospital, Msida, Malta
  4. 4Ear, Nose and Throat Department, Mater Dei Hospital, Msida, Malta
  1. Correspondence to Dr Gerd Xuereb; gerdxuereb{at}


Sporadic Burkitt’s lymphoma affecting the nasopharyngeal region is an extremely rare disease, especially in infants. We describe the case of a 2-year-old boy who presented to the ear, nose and throat department with a history of snoring, blood-stained rhinorrhoea and symptoms consistent with upper respiratory tract infections. Physical examination revealed massive cervical lymphadenopathy. MRI of the head and neck showed a mass lesion in the nasopharynx with bilateral lymph node enlargement. Debulking of the mass was performed and biopsies were sent for histology, which confirmed Burkitt’s lymphoma. The patient was treated with complex chemotherapy and had a good clinical response. The patient remains in remission after 6 years.

  • paediatrics
  • paediatric oncology
  • ear, nose and throat/otolaryngology
  • haematology (incl blood transfusion)
  • infant health

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  • Contributors The patient was under the care of the firm of CB. GX, JB and KA followed up the patient. GX and JB conducted a review of the current literature and on previously reported cases of Burkitt’s lymphoma. The findings were critically analysed and evaluated by GX, JB and KA. The case report was written by GX and JB. KA critically revised the case report. The study was supervised by CB. All authors read and approved the final version submitted for publication.

  • Funding The authors have not declared a specific grant for this research from any funding agency in the public, commercial or not-for-profit sectors.

  • Competing interests None declared.

  • Patient consent for publication Parental/guardian consent obtained.

  • Provenance and peer review Not commissioned; externally peer reviewed.

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