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Case report
Intraoperative mitomycin C and cryotherapy as adjunct therapy for recurrent lobular capillary haemangioma of conjunctiva
  1. Suwarna Suman1 and
  2. Arushi Kumar2
  1. 1Department of Ophthalmology, All India Institute of Medical Sciences, Jodhpur, Rajasthan, India
  2. 2Dr S N Medical College and MDM Hospital, Jodhpur, Rajasthan, India
  1. Correspondence to Dr Suwarna Suman; suwarnasuman{at}


Recurrence of lobular capillary haemangioma of conjunctiva after surgical excision is rare but sometimes it may be difficult to manage multiple recurrences. A 31-year-old female patient presented with recurrent polypoid conjunctival lobular capillary haemangioma. Excisional biopsy was performed, followed by eye drop mitomycin C 0.04% four times a day for 1 week postoperatively. She reported again after 3 months with recurrence of vascular elongated nodular lesion. Excision of the mass with application of mitomycin C 0.02% intraoperatively for 1 min and cryotherapy using double thaw technique of the peripheral conjunctival margin was done. The histopathological examination confirmed the recurrence of lobular capillary haemangioma. On review, 1 year after treatment there was no evidence of recurrence. A combined use of cryotherapy and intraoperative mitomycin C as adjunctive therapy after surgical excision can successfully prevent further recurrence without any adverse effect.

  • hemangioma
  • capillary
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  • Contributors Both the authors contributed to this article. SS wrote the manuscript, collected the references, revised the manuscript and approved the finalised manuscript. AK was involved in writing, revision and the final approval of the manuscript. Both the authors were involved in the management and follow-up of the patient.

  • Funding The authors have not declared a specific grant for this research from any funding agency in the public, commercial or not-for-profit sectors.

  • Competing interests None declared.

  • Patient consent for publication Obtained.

  • Provenance and peer review Not commissioned; externally peer reviewed.

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