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Case report
Treatment of recalcitrant orbital inflammatory syndrome with plasmapheresis therapy
  1. Yasaira Rodriguez Torres,
  2. Fereshteh Azad and
  3. Xihui Lin
  1. Ophthalmology, Kresge Eye Institute, Detroit, Michigan, USA
  1. Correspondence to Dr Yasaira Rodriguez Torres; yrodrigu{at}


Refractory idiopathic orbital inflammation (IOI) represents a management challenge due to its significant proportion of treatment failures. Currently, there are no established guidelines for recalcitrant IOI and majority of immunosuppressive agents have resulted in variable outcomes. Advancements of plasmapheresis therapy can play a significant role in ophthalmological diseases. This treatment has shown to produce a satisfactory therapeutic response in immune-mediated neurological conditions. In this case report, we share our successful experience with the use of plasmapheresis therapy in a patient with recalcitrant IOI.

  • eye
  • haematology (incl blood transfusion)

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  • Contributors YR, XL: planning, design and conception. YR, FA: data acquisition and analysis. YR, XL: interpretation of data. YR, FA: drafting the manuscript. YR, FA, XL: revising the manuscript critically for important intellectual content. YR, FA, XL: final approval of the version published.

  • Funding The authors have not declared a specific grant for this research from any funding agency in the public, commercial or not-for-profit sectors.

  • Competing interests None declared.

  • Patient consent for publication Obtained.

  • Provenance and peer review Not commissioned; externally peer reviewed.

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