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Case report
Supraglottic laryngeal sarcoidosis masquerading as supraglottitis
  1. Samuel Robert Leedman,
  2. Thomas Hendriks,
  3. Travis William Leahy and
  4. David Hall
  1. Otolaryngology Head and Neck Surgery, Fiona Stanley Hospital, Murdoch, Perth, Western Australia, Australia
  1. Correspondence to Dr Samuel Robert Leedman; samleedman{at}


Sarcoidosis is a rare multisystem disorder of unknown aetiology characterised by non-caseating granulomas in involved organs; it is a diagnosis of exclusion. Laryngeal involvement affects only 0.5%–5% of those with sarcoidosis. It is an uncommon but important cause of supraglottic inflammation and oedema and should be considered in the differential diagnosis in patients with supraglottitis. This case describes a 30-year-old man who presented with stridor and shortness of breath. Flexible nasendoscopic examination revealed a grossly oedematous, pale pink, diffusely hypertrophied epiglottis. Surgical biopsy revealed non-caseating granulomatous inflammation. In the context of exclusion of hepatitis, anti-neutrophil cytoplasmic antibody (ANCA) positivity, malignancy and mycobacterial infection, the diagnosis of supraglottic laryngeal sarcoid was made. He is being treated with azathioprine immunosuppression with symptomatic improvement.

  • ear, nose and throat/otolaryngology
  • otolaryngology/ENT

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  • Contributors All listed authors were involved with the clinical care of this patient's case. TH is a surgical service registrar, SRL a resident medical officer and TWL and DH both ENT surgical consultants looking after this patient whilst an inpatient and in the outpatient setting on follow-up in clinic. SRL wrote the manuscript with editorial assistance from the other three listed authors.

  • Funding The authors have not declared a specific grant for this research from any funding agency in the public, commercial or not-for-profit sectors.

  • Competing interests None declared.

  • Patient consent for publication Obtained.

  • Provenance and peer review Not commissioned; externally peer reviewed.

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