Article Text

Download PDFPDF
Case report
Yolk sac tumour of ovary with fever and overt hypothyroidism: rare clinical presentation
  1. Megha Kansara,
  2. Garima Yadav,
  3. Meenakshi Gothwal and
  4. Pratibha Singh
  1. Obstetrics and Gynecology, AIIMS Jodphur, Jodhpur, Rajasthan, India
  1. Correspondence to Dr Megha Kansara; kansara.megha66{at}


Yolk sac tumours of the ovary are rare and highly malignant germ cell tumours, which comprise of only 10%–15% of all malignant germ cell tumours. They have various clinical presentations most common being subacute pelvic pain and feeling of lump but sometimes high-grade fever can be one of the rare presentations. Here, we present a case report of a 26-year-old nulliparous woman with 36 weeks gravid uterus size advanced stage yolk sac tumour of one ovary with fever as main clinical presentation and overt hypothyroidism. We did staging laparotomy with total abdominal hysterectomy with bilateral salpingo-oophorectomy and omentectomy with multiple peritoneal biopsies. Postoperatively, we had started adjuvant chemotherapy. Since yolk sac tumours are highly aggressive tumours as they rapidly increase in size, their early diagnosis and appropriate surgical management is required particularly in young women where fertility sparing surgery is possible in early stage with good prognosis.

  • obstetrics and gynaecology
  • cancer - see oncology
  • pregnancy
  • cancer
  • chemotherapy

Statistics from


  • Contributors MK had planned, conduct, designed and analysed the case report. GY had edited, reported and planned. MG had interpreted and designed it. PS had analysed it and also acquisited the data.

  • Funding The authors have not declared a specific grant for this research from any funding agency in the public, commercial or not-for-profit sectors.

  • Competing interests None declared.

  • Patient consent for publication Obtained.

  • Provenance and peer review Not commissioned; externally peer reviewed.

Request Permissions

If you wish to reuse any or all of this article please use the link below which will take you to the Copyright Clearance Center’s RightsLink service. You will be able to get a quick price and instant permission to reuse the content in many different ways.