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Case report
Recurrent immune thrombocytopenia following different vaccines
  1. Estelle Morin1 and
  2. Manish Sadarangani2
  1. 1 Department of Pediatrics, University of Alberta, Edmonton, Alberta, Canada
  2. 2 Department of Pediatrics, The University of British Columbia, Vancouver, British Columbia, Canada
  1. Correspondence to Dr Manish Sadarangani, msadarangani{at}


A boy developed immune thrombocytopenia 2 weeks after receiving his measles-mumps-rubella and varicella vaccines at 12 months of age. He then had a recurrent episode 1 week after the booster doses of his quadrivalent diphtheria-tetanus-pertussis-polio, pneumococcal and meningococcal group C vaccines at 5 years of age. On both the occasions he required hospitalisation and treatment with intravenous immunoglobulin. He received other vaccines, before and in between, without any adverse events. Future vaccines are to be determined on an individual risk-benefit basis and he will be reviewed at the age of 11 when his next routine immunisations are due.

  • vaccination/immunisation
  • haematology (incl Blood Transfusion)

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  • Contributors Both authors conceived the idea for the manuscript. MS was responsible for care of the patient. Both authors collected data for the manuscript. EM wrote the first draft of the manuscript. Both authors critically reviewed the manuscript and approved the final version for submission.

  • Funding The authors have not declared a specific grant for this research from any funding agency in the public, commercial or not-for-profit sectors.

  • Competing interests None declared.

  • Provenance and peer review Not commissioned; externally peer reviewed.

  • Patient consent for publication Obtained.