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Rare disease
Case report
Rare brown tumour of the mandible secondary to tertiary hyperparathyroidism in a renal transplant recipient
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  1. Aurélien M Guéroult1 and
  2. Malcolm Cameron2
  1. 1 Cambridge University Hospitals NHS Foundation Trust, Cambridge, UK
  2. 2 Oral and Maxillofacial Surgery, Cambridge University Hospitals NHS Foundation Trust, Cambridge, UK
  1. Correspondence to Mr Malcolm Cameron, malcolm.cameron{at}addenbrookes.nhs.uk

Abstract

Brown tumours are rare osteolytic lesions that occur secondary to hyperparathyroidism (HPT). In 2% of all cases, the craniofacial bones are affected, most frequently the mandible. HPT is classified according to aetiology into three types, of which tertiary HPT is the rarest. Here we present the case of a 42-year-old man who had received a renal transplant 16 years previously and was referred due to swelling on the right side of his jaw. An orthopantomogram revealed a multilocular radiolucency in the right body of the mandible. The bony lesion was treated by surgical enucleation. After histopathological examination of the lesion, the diagnosis of brown tumour of the mandible secondary to tertiary HPT was reached. The patient’s recovery was uneventful and follow-up radiography showed good bone healing.

  • calcium and bone
  • mouth
  • fluid electrolyte and acid-base disturbances
  • renal transplantation
  • oral and maxillofacial surgery

https://doi.org/10.1136/bcr-2019-231231

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    Footnotes

    • Contributors The case report was mostly written by AMG; MC read and edited the original report and is the supervising consultant.

    • Funding The authors have not declared a specific grant for this research from any funding agency in the public, commercial or not-for-profit sectors. With

    • Competing interests None declared.

    • Provenance and peer review Not commissioned; externally peer reviewed.

    • Patient consent for publication Obtained.