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Case report
Spontaneous splenic rupture in a patient with infectious mononucleosis
  1. Charlotte Ruth Baker and
  2. Sid Kona
  1. Emergency Department, Royal Free London NHS Foundation Trust, London, UK
  1. Correspondence to Dr Charlotte Ruth Baker, charlotte.baker{at}


We present a case of spontaneous, atraumatic splenic rupture secondary to Epstein-Barr virus (EBV) infection, in a young, female patient. Splenic rupture is a rare complication of EBV infection, but is associated with the highest mortality. Additionally, this case illustrates the diagnostic challenge in a patient presenting in atypical manner, with only left-sided pleuritic chest pain, and lacking any of the classical tonsillitis symptoms associated with EBV infection.

  • Emergency Medicine
  • Infection (gastroenterology)
  • Hepatitis Other
  • Infectious Diseases
  • Surgery

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  • Contributors CRB and SK were both involved in the clinical care of the patient in this case. The case report was drafted and finalised by CRB, with the guidance and revisions by SK.

  • Funding The authors have not declared a specific grant for this research from any funding agency in the public, commercial or not-for-profit sectors.

  • Competing interests None declared.

  • Provenance and peer review Not commissioned; externally peer reviewed.

  • Patient consent for publication Obtained.