Sarcoidosis is a multisystem disorder characterised by non-caseating granulomas that typically affect the lungs, skin and lymph nodes. Sarcoidosis has been associated with various cancers, and we describe the case of a patient with systemic sarcoidosis associated with testicular seminoma. This was originally diagnosed as stable sarcoid-like reaction. He subsequently presented with ventricular tachycardia. Cardiovascular MRI suggested cardiac sarcoidosis, which was confirmed by myocardial biopsy. This case highlights the association between some types of cancer and sarcoidosis. In addition, it highlights the importance of close follow-up for patients with a history of malignancy to monitor for sarcoid-like reactions and sarcoidosis, which are often difficult to differentiate clinically.
- cardiovascular medicine
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Contributors All authors included agree that they have made: substantial contributions to the conception or design of the work, or the acquisition, analysis or interpretation of data; have been involved in drafting the work or revising it critically for important intellectual content; have given final approval of the version published; have an agreement to be accountable for all aspects of the work in ensuring that questions related to the accuracy or integrity of any part of the work are appropriately investigated and resolved. Specifically, the authors have contributed the following: DB has been involved in writing the manuscript, in particular researching and writing the pathophysiology of sarcoidosis and sarcoid-like reactions of the discussion section. He has also been involved in critical revision of final draft, preparation of figures, contacting patient in the initial drafts and managing the project overall. DS has been responsible for the conception of manuscript, preparation of figures and interpretation of cardiac MRI and its clinical significance. He has also provided critical review of final draft and provided his clinical and research experience in editing the final case report. PB has been involved with demonstrating the patients perspective, differential diagnosis and gaining consent from the patient. He has also been involved in editing the general manuscript. In addition his role has included finalising the document format and making it relative to the BMJ requirements for case reports. MW has been responsible for writing manuscript and has contributed to the preparation of figures and overall format.
Funding This study was funded by King’s College Hospital NHS Foundation Trust, http://dx.doi.org/10.13039/100010872. Grant number: 422939.
Competing interests None declared.
Provenance and peer review Not commissioned; externally peer reviewed.
Patient consent for publication Obtained.