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Case report
Sclerosing angiomatoid nodular transformation of the spleen
  1. Jiaying Liao1,
  2. Aya Musbahi1,
  3. Kaushik Dasgupta2,
  4. Herwig Thibaut3 and
  5. Bussa Gopinath1
  1. 1 General Surgery, North Tees and Hartlepool NHS Foundation Trust, Stockton-on-Tees, UK
  2. 2 Pathology, North Tees and Hartlepool NHS Foundation Trust, Stockton-on-Tees, UK
  3. 3 Radiology, North Tees and Hartlepool NHS Foundation Trust, Stockton-on-Tees, UK
  1. Correspondence to Dr Jiaying Liao, jessieliao9933{at}


The authors described a case of sclerosing angiomatoid nodular transformation of the spleen (SANT) in a 50-year-old woman presented with persistent neutrophilia and unintentional weight loss. An incidental splenic mass was initially found on abdominal ultrasound. It was found to be progressive in size and with high likelihood of central necrosis on further CT of abdomen and pelvis. The patient subsequently underwent an uneventful laparoscopic splenectomy. The splenic specimens were sent for laboratory analysis and the histopathological findings were highly suggestive of SANT. The patient then had routine surgical follow-ups and was eventually discharged with no further clinical concern.

  • radiology
  • surgery
  • gastrointestinal surgery
  • general surgery
  • pathology
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  • Contributors Conception and design of study: JL, AM; acquisition of data: AM, BG; analysis and/or interpretation of data: JL, KD, HT; drafting the manuscript: JL; revising the manuscript critically for important intellectual content: JL, AM, KD, HT, BG; approval of the version of the manuscript to be published: JL, AM, KD, HT, BG; agreement to be accountable for the article and to ensure that all questions regarding the accuracy or integrity of the article are investigated and resolved: JL, AM, KD, HT, BG.

  • Funding The authors have not declared a specific grant for this research from any funding agency in the public, commercial or not-for-profit sectors.

  • Competing interests None declared.

  • Provenance and peer review Not commissioned; externally peer reviewed.

  • Patient consent for publication Obtained.

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