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Onychocryptosis and asymptomatic external urethritis as complications of oral isotretinoin therapy


This case report presents a patient who, while undergoing oral isotretinoin therapy for acne vulgaris, developed onychocryptosis and asymptomatic external urethritis. These uncommon adverse events are not well-documented in medical literature. While his urethritis spontaneously resolved, his onychocryptosis symptoms necessitated surgical intervention. This report illustrates both cosmetic and functional adverse effects of isotretinoin and provides insight into the progression of these reactions over time.

  • dermatology
  • skin
  • unwanted effects / adverse reactions
  • general practice / family medicine
  • urinary and genital tract disorders
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