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Varicella meningitis with concomitant genital shingles in an adolescent
  1. Shi Hua Chan1,
  2. Koh Cheng Thoon2 and
  3. Nandhakumar Nagarajan1
  1. 1 General Paediatrics, KK Women’s and Children’s Hospital, Singapore
  2. 2 Infectious Disease Service, Department of Paediatrics, KK Women’s and Children’s Hospital, Singapore
  1. Correspondence to Dr Shi Hua Chan, shihua.chan{at}


This case describes an uncommon presentation of herpes zoster in an adolescent with viral meningitis and concomitant genital shingles. A 15-year-old immunocompetent girl with background of well-controlled Graves’ disease presented with 3 days of fever, frontal headache, terminal neck stiffness and photophobia. This was preceded by 4 days of pain and itch over vaginal and anal region. She had one dose of varicella vaccination at 18 months old and developed mild primary varicella infection around 5 years of age. Varicella zoster virus DNA was detected both in cerebrospinal fluid and in vesicles over her right labial majora. While there is no international consensus on the recommended duration of treatment for zoster with neurological complications, she was treated with intravenous acyclovir for 10 days with good clinical response. Her fever, headache and neck stiffness resolved after 2 days and genital lesions resolved after 9 days of antiviral therapy.

  • meningitis
  • paediatrics
  • dermatology
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  • Contributors SHC was involved in the conceptualisation and writing of the manuscript. NN and KCT were involved in the review and editing of the manuscript.

  • Funding The authors have not declared a specific grant for this research from any funding agency in the public, commercial or not-for-profit sectors.

  • Competing interests None declared.

  • Provenance and peer review Not commissioned; externally peer reviewed.

  • Patient consent for publication Obtained.

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