Thymoma-associated multiorgan autoimmunity is a relatively new term to describe the rare paraneoplastic syndrome that complicates thymoma, which can involve the thyroid, liver and intestine in addition to the skin. The pathology often indicates a graft-versus-host-like pattern commonly observed in recipients of an allogeneic haematopoietic cell transplant. We report a case of type B2 and B3 thymoma with invasion to the lung and pleura in a patient who presented with oral lichen planus and graft-versus-host-like erythroderma. The cutaneous lesions improved after complete resection of the thymoma in combination with systemic glucocorticoids, which was subsequently complicated by cytomegalovirus pneumonitis.
- cardiothoracic surgery
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Contributors Conception and design of the work: C-TH, J-SC. Data collection: C-TH, J-SC. Data analysis and interpretation: C-TH, J-SC. Drafting the article: C-TH. Critical revision of the article: T-FT, M-SH. Final approval of the article: C-TH, J-SC, T-FT, M-SH.
Funding The authors have not declared a specific grant for this research from any funding agency in the public, commercial or not-for-profit sectors.
Competing interests None to declare
Ethics approval This case report was waived for ethics approval.
Provenance and peer review Not commissioned; externally peer reviewed.
Patient consent for publication Obtained.
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