Article Text
Abstract
A 70-year-old man reported progressive weight loss, fatigue and a generalised rash. The rash was consistent with necrolytic migratory erythema, further investigations were performed and the patient was diagnosed with a mass in the tail of the pancreas, in keeping with a localised glucagonoma. Somatostatin analogue therapy was started for symptom control, leading to complete resolution of the skin rash and an improvement in constitutional symptoms. Subsequently, the pancreatic lesion was excised, and pathology assessment confirmed the diagnosis of well-differentiated neuroendocrine tumour with high expression of glucagon compatible with glucagonoma.
- pancreatic cancer
- cancer intervention
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Footnotes
Contributors CS and RAH have contributed to the data collection, bibliographic review and drafting of the case report. AL has contributed to obtaining patient consent and pictures, data collection, bibliographic review and drafting of the case report.
Funding Dr Angela Lamarca was partly funded by The Christie Charity.
Competing interests CS received travel and educational support from Ipsen, Roche, Amgen, MSD, Novartis. AL received travel and educational support from Ipsen, Pfizer, Bayer, AAA, SirtEx, Novartis and Delcath; speaker honoraria from Merck, Pfizer and Ipsen; advisory honoraria from EISAI and Nutricia and was also a member of the Knowledge Network and NETConnect Initiatives funded by Ipsen.
Provenance and peer review Not commissioned; externally peer reviewed.
Patient consent for publication Obtained.