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A relapse of POEMS syndrome presenting as acute kidney injury
  1. David Owen Rees1,
  2. David Hywel Thomas2,
  3. Nilima Parry-Jones3 and
  4. Gareth Roberts1
  1. 1 Nephrology and Transplant Department, University Hospital of Wales, Cardiff, UK
  2. 2 Department of Pathology, University Hospital of Wales, Cardiff, UK
  3. 3 Department of Haematology, Aneurin Bevan University Health Board, Abergavenny, UK
  1. Correspondence to Dr David Owen Rees, davidowenrees{at}


Peripheral neuropathy, organomegaly, endocrinopathy, monoclonal protein and skin changes (POEMS) syndrome is a rare disease, and only in a minority of cases, causes an impairment of kidney function. Here, we describe a case of a 55-year-old man with a history of POEMS syndrome who presented with acute kidney injury following a routine blood test. On further investigation, a relapse in POEMS syndrome was diagnosed, uniquely isolated to renal involvement.

  • haematology (incl blood transfusion)
  • acute renal failure
  • proteinurea

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  • Contributors DOR conducted literature review and wrote case report. DHT interpreted slides and provided images of slides. NP-J provided haematology guidance. GR supervised and edited case report.

  • Funding The authors have not declared a specific grant for this research from any funding agency in the public, commercial or not-for-profit sectors.

  • Competing interests None declared.

  • Provenance and peer review Not commissioned; externally peer reviewed.

  • Patient consent for publication Obtained.

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