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Hyponatraemia presenting as reversible cerebellar ataxia in Addison’s disease
  1. Judah Nijas Arul,
  2. Mani Rajkumar and
  3. Lakshmanan Suja
  1. General Medicine, Sri Ramachandra Institute of Higher Education and Research, Chennai, Tamil Nadu, India
  1. Correspondence to Dr Lakshmanan Suja, suja.lakshmanan{at}


Addison’s disease is a common endocrinopathy often diagnosed in patients presenting with hyponatraemia. Cerebellar ataxia as a presentation of hyponatraemia is extremely rare. A 42-year-old man presented with vomiting, fever, ataxic gait and scanning type of dysarthria. Clinical examination revealed signs suggestive of isolated cerebellar involvement. Patient was found to have severe hyponatraemia and serum cortisol was found to be extremely low while MRI brain was found to be normal. Corticosteroid therapy was initiated and cerebellar ataxia was resolved following normalisation of sodium levels.

  • adrenal disorders
  • brain stem/cerebellum

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  • Contributors JNA: primary author of the manuscript. MR: primary consultant and final reviewer of the manuscript. LS: primary reviewer of manuscript and assistant consultant.

  • Funding The authors have not declared a specific grant for this research from any funding agency in the public, commercial or not-for-profit sectors.

  • Competing interests None declared.

  • Provenance and peer review Not commissioned; externally peer reviewed.

  • Patient consent for publication Obtained.

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