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Leucocyte adhesion defect presenting as fulminant sepsis in a new born


We present a term neonate with severe sepsis, presenting on day 10 of life. The neonate presented with bilateral purulent eye discharge and hepatosplenomegaly. On investigation, persistent leucocytosis was observed and thus the possibility of leucocyte adhesion defect was considered. Flow cytometry confirmed the diagnosis.

  • Neonatal Health
  • Neonatal And Paediatric Intensive Care
  • Materno-fetal Medicine
  • Infant Health

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