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Leucocyte adhesion defect presenting as fulminant sepsis in a new born
  1. Vishal Gupta1,
  2. Aakash Pandita2,
  3. Astha Panghal2 and
  4. Anish Pillai3
  1. 1 Neonatology, Neonest Hospital, New Delhi, India
  2. 2 Neonatology, Sanjay Gandhi Post Graduate Institute of Medical Sciences, Lucknow, Uttar Pradesh, India
  3. 3 Division of Neonatology, BC Women’s and Children’s Hospital, Vancouver, Canada
  1. Correspondence to Dr Aakash Pandita, aakash.pandita{at}


We present a term neonate with severe sepsis, presenting on day 10 of life. The neonate presented with bilateral purulent eye discharge and hepatosplenomegaly. On investigation, persistent leucocytosis was observed and thus the possibility of leucocyte adhesion defect was considered. Flow cytometry confirmed the diagnosis.

  • Neonatal Health
  • Neonatal And Paediatric Intensive Care
  • Materno-fetal Medicine
  • Infant Health

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  • Contributors AaP, VG and AsP wrote the initial manuscript. VG, AaP did the final corrections and AnP, AaP helped in critical appraisal. All authors accepted the final manuscript.

  • Funding The authors have not declared a specific grant for this research from any funding agency in the public, commercial or not-for-profit sectors.

  • Competing interests None declared.

  • Provenance and peer review Not commissioned; externally peer reviewed.

  • Patient consent for publication Parental/guardian consent obtained.

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