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Sclerosing mucoepidermoid carcinoma with eosinophilia of thyroid
  1. Haissan Iftikhar1,
  2. Muhammad Sohail Awan1,
  3. Shayan Khalid Ghaloo1 and
  4. Saira Fatima2
  1. 1 Department of Surgery, Aga Khan University, Karachi, Pakistan
  2. 2 Department of Pathology, Aga Khan University, Karachi, Pakistan
  1. Correspondence to Dr Haissan Iftikhar, haissaniftikhar{at}


Sclerosing mucoepidermoid carcinoma of the thyroid was first reported in 1991. This tumour type may develop as associated to Hashimoto thyroiditis. There are two variants of mucoepidermoid carcinoma of thyroid. The conventional and the sclerosing variants. Sclerosing mucoepidermoid carcinoma with eosinophilia of thyroid (SCME) has recently been recognised as a separate disease entity by the WHO. We report a case of SCME in a 62-year-old male patient who presented with a painless anterior neck swelling. Total thyroidectomy was performed, and no adjuvant treatment administered. The patient remained disease free up until 10 months of follow-up. Approximately 40 cases are reported in literature. We report the second case of SCME in Asian men. Sclerosing mucoepidermoid carcinoma with eosinophilia of thyroid should be differentiated from the conventional mucoepidermoid carcinoma. Patients should also be advised of long-term follow-up for surveillance.

  • ear, nose and throat/otolaryngology
  • thyroid disease

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  • Contributors HI formulated the case report. MSA approved the final version of the manuscript. SKG gathered the histopathology images and helped write the manuscript. SF provided the histological images and the description.

  • Funding The authors have not declared a specific grant for this research from any funding agency in the public, commercial or not-for-profit sectors.

  • Competing interests None declared.

  • Provenance and peer review Not commissioned; externally peer reviewed.

  • Patient consent for publication Obtained.