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An unusual cause of paraesthesia in a neo-adjuvant gastro-oesophageal cancer
  1. Sarah Derby1,
  2. Janet Graham2 and
  3. David McIntosh2
  1. 1 Clinical Oncology, Beatson West of Scotland Cancer Centre, Glasgow, UK
  2. 2 Medical Oncology, Beatson West of Scotland Cancer Centre, Glasgow, UK
  1. Correspondence to Dr Sarah Derby, Sarah.Derby{at}


There is ongoing debate about the best neo-adjuvant strategy for localised resectable oesophageal cancer, however chemotherapy is often employed. Both oesophageal cancer and cisplatin carry an increased risk of thrombosis. Here, we look at an unusual finding in a previously fit woman who presented following neo-adjuvant chemotherapy for resectable oesophageal cancer with increasing difficulty in walking and lower limb paraesthesia. This case looks particularly at the diagnostic challenge and concerns raised in a patient undergoing radical treatment as well as the challenge of complications secondary to treatment with chemotherapy. Willingness to reassess and revisit is a vital part of the diagnostic process. Vascular complications of a disease can be notorious to diagnose and, as in this case can mimic arguably more logical diagnoses. Cancer care provides the unique challenge of investigating unusual presentations related both to disease and treatment.

  • cancer intervention
  • radiology
  • oesophageal cancer
  • oncology
  • venous thromboembolism
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  • Contributors SD (Clinical Oncology registrar) was responsible for the writing of this case report and obtaining consent from the patient. JG (Medical Oncology consultant) and DM (Clinical Oncology consultant) supervised the writing of the above case and were involved in the care of the patient that this case was written about. SD retrieved consent from the patient to publish this report and the CT pictures attached. Both JG and DM reviewed the manuscript of the above case prior to submission and the attached images.

  • Funding The authors have not declared a specific grant for this research from any funding agency in the public, commercial or not-for-profit sectors.

  • Competing interests None declared.

  • Provenance and peer review Not commissioned; externally peer reviewed.

  • Patient consent for publication Obtained.

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