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Throat discomfort after orotracheal or nasotracheal procedures is relatively common, and usually due to pharyngeal irritation. We describe a rare case of uvular necrosis as a cause of throat discomfort after endotracheal intubation (shown in figure 1).
A 69-year-old man with a medical history significant for severe aortic stenosis, coronary artery disease and hypertension presented to the emergency department with chief complaint of shortness of breath. Patient reported that he over-exerted himself at the gym and felt so short of breath that he had to call emergency medical staff. Patient was brought to the emergency department where he was found to have a systolic blood pressure of 230 mm Hg and diastolic blood pressure of 120 mm Hg. Chest X-ray was significant for pulmonary oedema. Non-invasive positive pressure ventilation and nitroglycerine drip were initiated. Symptoms did not improve, and he was intubated. After receiving etomidate and rocuronium, Macintosh blades 3 were used to introduce a 7.5-French endotracheal tube. Intubation was successful in first attempt and chest X-ray confirmed proper position precluding the need to readjust the endotracheal tube. In the intensive care unit, he was treated with nicardipine drip and diuresis for pulmonary oedema. He was extubated after 36 hours. A few hours later he reported throat discomfort, feeling his uvula was larger and touching the back of his tongue. On examination, pharyngeal erythema and blanching of the lower half of the uvula were noted, consistent with uvular necrosis. Patient received acetaminophen and lozenges for symptom management. He was discharged home and on follow-up 1 week later patient reported that his symptoms had resolved and the necrosed part of uvula had sloughed off.
Uvular necrosis has been described after endotracheal intubation, upper gastrointestinal endoscopy, bronchoscopy via nasal approach and vigorous suctioning. Emmett et al suggested that men are at a higher risk of developing uvular oedema or necrosis owing to the bulkier tongue and palate with significantly more non-fat tissue in the neck.1 2 Patients with elongated uvula are also predisposed to uvular necrosis.3 It has been hypothesised that compression of the uvula against the pharynx or hard palate results in impaired blood flow and eventually necrosis.4 5 Interestingly, uvular necrosis has been seen in procedures lasting only 15 min.6 Most of the cases described had scopes/tubes inserted orally, however this complication was also seen in patient who underwent nasal bronchoscopy3; the supine positioning of the patient was thought to be responsible for this complication.
Case reports have suggested symptomatic management with acetaminophen, steroids, antihistamines and topical epinephrine. The necrotic portion of the uvula sloughs off within 2 weeks without any further complications. Surgical resection of necrosed uvula was tried in one case report7; immediate resolution of foreign body sensation was achieved; however, sore throat persisted for more than a week.
It is suggested that during bronchoscopy, intubation or endoscopy, the tube or scope should be placed to one side of the midline to prevent damage to the uvula.3 Blind and aggressive suctioning should also be avoided.6
Uvular necrosis may be a cause of throat discomfort after endotracheal intubation.
Symptomatic management with acetaminophen, steroids, antihistamines and topical epinephrine is generally sufficient. The necrotic portion of the uvula usually sloughs off within 2 weeks.
It is suggested that during bronchoscopy, intubation or endoscopy, the tube or scope should be placed to one side of the midline to prevent damage to the uvula.
Contributors The case report was written by MHI. The case report was edited by FIR and HL-F. The patient was in the direct care of MHI.
Funding The authors have not declared a specific grant for this research from any funding agency in the public, commercial or not-for-profit sectors.
Competing interests None declared.
Provenance and peer review Not commissioned; externally peer reviewed.
Patient consent for publication Obtained.
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