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CASE REPORT
Isolated growth hormone deficiency presenting with recurrent hypoglycaemia in a toddler
  1. Hiya Boro1,
  2. Alpesh Goyal2 and
  3. Rajesh Khadgawat2
  1. 1 Endocrinology and Metabolism, All India Institute of Medical Sciences, New Delhi, India
  2. 2 Endocrinology, All India Institute of Medical Sciences, New Delhi, India
  1. Correspondence to Dr Alpesh Goyal, alpeshgoyal89{at}gmail.com

Abstract

Hypoglycaemia in infants and children is caused by a number of endocrine and metabolic defects, some of which are unique to this age group. Growth hormone deficiency (GHD) has been rarely reported as a cause of recurrent fasting hypoglycaemia in children. An 18-month-old male child presented to us for evaluation of neuroglycopenic symptoms caused by recurrent episodes of fasting hypoglycaemia. Laboratory evaluation revealed ketotic hypoinsulinaemic hypoglycaemia. The child was diagnosed to have GHD on the basis of two failed stimulation tests. A detailed work-up for metabolic and other hormonal causes of hypoglycaemia was negative. We present the case for its rarity and to highlight the importance of a detailed metabolic and hormonal assessment in evaluation of childhood hypoglycaemia.

  • endocrine system
  • paediatrics (drugs and medicines)
  • pituitary disorders
  • metabolic disorders
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Footnotes

  • Contributors HB, AG and RK diagnosed and managed the patient, carried out a literature search, collected data about the case and drafted the manuscript. All the authors reviewed and revised the final manuscript.

  • Funding The authors have not declared a specific grant for this research from any funding agency in the public, commercial or not-for-profit sectors.

  • Competing interests None declared.

  • Provenance and peer review Not commissioned; externally peer reviewed.

  • Patient consent for publication Parental/guardian consent obtained.

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