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Exophytic primary gastric squamous cell carcinoma and H. pylori gastritis
  1. Kehua Zhou1,
  2. Aniqa Faraz1,
  3. Minoti Magotra2 and
  4. Muhammad Tahir1
  1. 1 Catholic Health Internal Medicine Training Program, University at Buffalo Jacobs School of Medicine and Biomedical Sciences, Buffalo, New York, USA
  2. 2 Mercy Hospital of Buffalo, Buffalo, New York, USA
  1. Correspondence to Dr Kehua Zhou, kehuazho{at}


Primary gastric squamous cell carcinoma (SCC) is rare, and the simultaneous Helicobacter pylori infection has not been reported in the literature. Here, we presented a patient with concurrent H. pylori gastritis and primary gastric SCC. A 54-year-old Hispanic man presented with diarrhoea, chills, night sweats and weight loss of 16 lbs for the previous 6 weeks. Abdominal CT revealed large exophytic mass from the stomach infiltrating multiple organs. Biopsy was performed and histology showed squamoid features. Immunohistochemistry stain was positive for p40, CK5/6, CK7 and Helicobacter type organisms. Patient was diagnosed with primary gastric SCC and has been receiving chemotherapy. We also reviewed the diagnosis, prognosis and treatment of primary gastric SCC.

  • gastrointestinal system
  • GI bleeding
  • gastric cancer
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  • Contributors KZ wrote the majority of the article; AF wrote a portion of the manuscript; MM and MT provided constructive feedback during the manuscript preparation and drafting process.

  • Funding The authors have not declared a specific grant for this research from any funding agency in the public, commercial or not-for-profit sectors.

  • Competing interests None declared.

  • Provenance and peer review Not commissioned; externally peer reviewed.

  • Patient consent for publication Obtained.

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