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Malignant melanoma arising from an end ileostomy
  1. Richard William Donald Gilbert1,
  2. Harry Myles Harvey2 and
  3. Carolyn Nessim1
  1. 1 General Surgery, Ottawa General Hospital, Ottawa, Ontario, Canada
  2. 2 Department of Medicine, Royal College of Surgeons in Ireland, Dublin, Ireland
  1. Correspondence to Dr Richard William Donald Gilbert, richard.wd.gilbert{at}


A 65-year-old woman with a history of proctocolectomy and end ileostomy for ulcerative colitis was referred to our clinic with a slowly growing mass around her ileostomy. She did not report any systemic symptoms. On examination, an exophytic mass was observed around her ileostomy and hard lymph nodes palpated in her groins bilaterally. Punch biopsy of the lesion established a diagnosis of invasive melanoma. Positron emission tomography revealed regional metastatic lymphadenopathy in the right axilla and both groins. There was no evidence of distant metastatic disease. The patient then underwent wide local excision of her ileostomy with bowel resection and ileostomy re-siting, bilateral complete ilioinguinal lymphadenectomy and a right Level III axillary dissection. She is doing well postoperatively and receiving adjuvant systemic therapy with BRAF and MEK inhibitors, now 17 months later with no signs of recurrent disease.

  • surgical oncology
  • oncology
  • dermatology
  • skin cancer

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  • Contributors RWDG, HMH and CN were involved in the drafting and editing of the manuscript. RWDG and CN were involved in the care of the patient mentioned.

  • Funding The authors have not declared a specific grant for this research from any funding agency in the public, commercial or not-for-profit sectors.

  • Competing interests None declared.

  • Provenance and peer review Not commissioned; externally peer reviewed.

  • Patient consent for publication Obtained.