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An unusual cause of gastrointestinal bleed in patients with liver cirrhosis
  1. Anand V Kulkarni1,
  2. Manoj Kumar Sharma1,
  3. Kapil Dev Jamwal1 and
  4. Asit Arora2
  1. 1 Hepatology, Institute of Liver and Biliary Sciences, New Delhi, India
  2. 2 Hepatobiliary Surgery, Institute of Liver and Biliary Sciences, New Delhi, India
  1. Correspondence to Dr Anand V Kulkarni, anandvk90{at}


Acute upper gastrointestinal (UGI) bleeding in cirrhosis has been classically linked to variceal rupture, although peptic ulcer and portal hypertensive gastropathy-related bleed are not uncommon. Gastrointestinal stromal tumour (GIST) is the most common mesenchymal tumour and may also present as UGI bleed; however, there are no reports of GIST presenting as UGI bleed in patients with cirrhosis. Here, we report three cases of GIST who had presented with UGI bleed and were successfully managed with surgical excision and are tolerating imatinib without recurrence.

  • gastrointestinal system
  • GI bleeding
  • cirrhosis
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  • Contributors AVK and KDJ made the study concept and design. Data acquisition and drafting of manuscript by AVK. Compilation and critical revision by MKS. Surgery and surgical aspects by AA. All members approved final draft.

  • Funding The authors have not declared a specific grant for this research from any funding agency in the public, commercial or not-for-profit sectors.

  • Competing interests None declared.

  • Provenance and peer review Not commissioned; externally peer reviewed.

  • Patient consent for publication Obtained.

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