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Brugada pattern: a comprehensive review on the demographic and clinical spectrum
  1. Hassan Abbas,
  2. Sohaib Roomi,
  3. Waqas Ullah,
  4. Asrar Ahmad and
  5. Ganesh Gajanan
  1. Internal Medicine, Abington Jefferson Health, Abington, Pennsylvania, USA
  1. Correspondence to Dr Waqas Ullah, waqasullah.dr{at}


A prominent coved or saddle-shaped ST-segment elevation followed by T wave changes in V1-V3 and in the absence of other identifiable cause is termed as Brugada pattern. This pattern in the presence of documented ventricular arrhythmias or its symptoms (syncope, seizure) or significant family for sudden cardiac death or abovementioned ECG changes is called Brugada syndrome. Here we present a comprehensive literature review on the precipitation factors of Brugada syndrome/pattern by various stimuli, its presentation, associations, management and outcomes. We are also presenting a unique case of Brugada pattern where the patient’s Brugada pattern was unmasked at an extreme old age by infection.

  • cardiovascular medicine
  • arrhythmias

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  • Contributors SR performed data extraction and helped in references. HA managed the case and wrote presentation. WU wrote discussion. AA reviewed the article. GG did a critical review and supervision.

  • Funding The authors have not declared a specific grant for this research from any funding agency in the public, commercial or not-for-profit sectors.

  • Competing interests None declared.

  • Provenance and peer review Not commissioned; externally peer reviewed.

  • Patient consent for publication Next of kin consent obtained.

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