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Malignant intestinal obstruction during twin pregnancy: surgical resection of a myxoid liposarcoma without induction of labour
  1. Christoph Paasch1,
  2. Annette Isbruch2,
  3. Martin W Strik1 and
  4. Robert Siegel1,3
  1. 1 General, Visceral and Oncology Surgery, Helios Klinikum Berlin-Buch, Berlin, Germany
  2. 2 Obstetrics and Gynaecology, Helios Klinikum Berlin-Buch, Berlin, Germany
  3. 3 Faculty of Health, Witten/Herdecke University, Witten, Germany
  1. Correspondence to Dr Christoph Paasch, christoph.paasch{at}


Myxoid liposarcoma (MLS) represents one of the three main morphological subgroups of liposarcomas. Extrapulmonary recurrence to the retroperitoneum and abdomen is common in MLS. A pregnant patient was referred to our hospital due to abdominal pain and obstipation. In the past, she had received a multimodal treatment of an MLS of the left dorsal thigh. Now, MRI revealed a 14.6×10.1×12.4 cm-sized tumour adjacent to the uterus with a known twin pregnancy (26th week). We performed surgery under tocolytic therapy. The tumour has been completely removed. The histopathological examination revealed a nodular manifestation of a moderately differentiated MLS arising from the mesentery. Eleven weeks later, our patient delivered healthy twins. This is the first report of surgical resection of MLS during a twin pregnancy. With a multidisciplinary approach and a concerted treatment by surgeons and obstetricians, surgical resection resolved malignant intestinal obstruction and enabled an uncomplicated continuation of pregnancy.

  • surgical oncology
  • general surgery
  • gastrointestinal surgery
  • pregnancy
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  • Contributors All authors participated in the conception and design of the study. CP and RS drafted the manuscript. All authors participated in the care of the patient. All authors were involved in the final editing and read and approved the final manuscript.

  • Funding The authors have not declared a specific grant for this research from any funding agency in the public, commercial or not-for-profit sectors.

  • Competing interests None declared.

  • Provenance and peer review Not commissioned; externally peer reviewed.

  • Patient consent for publication Obtained.

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