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Nocardial endocarditis in native aortic valve with nocardial sepsis in a case of breast cancer
  1. Sudeep Gupta1,
  2. Seema Gulia1,
  3. Ram abhinav Kannan1,
  4. Camilla Rodrigues2,
  5. Jayesh Dhareshwar3 and
  6. Amit Vora4
  1. 1 Department of Medical Oncology, Tata Memorial Centre, Mumbai, Maharashtra, India
  2. 2 Department of Microbiology, Hinduja Hospital, Mumbai, Maharashtra, India
  3. 3 Department of Cardiothoracic Surgery, Jupiter Hospital, Mumbai, Maharashtra, India
  4. 4 Glenmark Cardiac Centre, Mumbai, Maharashtra, India
  1. Correspondence to Dr Seema Gulia, drseemagulia10{at}


Central venous catheter-associated bacteraemia caused by Nocardia species is very rare; the diagnosis of nocardiosis in patients with cancer is challenging because its clinical presentation is varied, sometimes mimicking metastases, and the high index of clinical suspicion is required for prompt institution of therapy. Herein, we report a case of nocardial sepsis with native aortic valve endocarditis in a patient with breast cancer in whom multidisciplinary team involvement and prompt initiation of therapy have led to successful outcome.

  • infections
  • oncology
  • breast cancer
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  • Contributors SuG and SeG involved in patient management, drafting and final approval of manuscript. RAK: drafting manuscript and final approval. CR (microbiologist who made the diagnosis): final approval of manuscript. JD is cardiovascular surgeon who did aortic valve replacement and final approval of manuscript. AV is cardiologist who was actively involved in management and final approval of manuscript.

  • Funding The authors have not declared a specific grant for this research from any funding agency in the public, commercial or not-for-profit sectors.

  • Competing interests None.

  • Provenance and peer review Not commissioned; externally peer reviewed.

  • Patient consent for publication Obtained.

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