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Late-onset group B streptococcus infections and severe bronchopulmonary dysplasia in an extremely preterm born infant
  1. Raymond Suffolk1,
  2. Lone Agertoft2,
  3. Malene Johansen3 and
  4. Gitte Zachariassen3
  1. 1 Paediatric Department, Hospital of Southern Jutland, Aabenraa, Denmark
  2. 2 Paediatric, H.C. Andersens Children Hospital, Odense, Denmark
  3. 3 Neonatal Intensive Care Unite, H.C. Andersen Child Hospital, Odense, Denmark
  1. Correspondence to Raymond Suffolk, raymond.suffolk{at}


This case report is about a boy born extremely preterm at gestational age of 24 weeks, with extremely low birth weight, developing severe bronchopulmonary dysplasia and in need of mechanical ventilation for 155 days. He also had five recurrent infections with group B streptococcus (GBS) within 4 months from birth, and his respiratory condition clearly deteriorated with every GBS infection. It was difficult to wean him from mechanical ventilation. Finally he was extubated when he was 7 months old and kept out of mechanical ventilation after receiving high-dose methylprednisolone, given according to international recommendations. After GBS was cultured for the fifth time, he received oral rifampicin along with intravenous penicillin and after this treatment, GBS did not occur again. At the age of 22 months, the boy no longer needed any respiratory support and he was about 6 months late in his neurological development.

  • neonatal intensive care
  • neonatal health
  • mechanical ventilation
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  • Contributors RS: main author of text and tables. LA: provider of information and references regarding pulmonary complications. Have written part of the text regarding pulmonary problems. MJ: major contributor of case presentation. GZ: the main guidance counselor.

  • Funding The authors have not declared a specific grant for this research from any funding agency in the public, commercial or not-for-profit sectors.

  • Competing interests None declared.

  • Provenance and peer review Not commissioned; externally peer reviewed.

  • Patient consent for publication Obtained.

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