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Benign metastasising leiomyoma presenting with respiratory distress
  1. Robert Stabler,
  2. Adnan Azim and
  3. Dawn Edwards
  1. Respiratory Medicine Department, Royal Bournemouth and Christchurch Hospitals NHS Foundation Trust, Bournemouth, Dorset, UK
  1. Correspondence to Dr Robert Stabler, stabler{at}


Benign metastasising leiomyoma (BML) is a rare gynaecological tumour which most commonly presents with incidental lung nodules. Here, we present a case of BML in which a 43-year-old woman was admitted in respiratory distress. She was found to have widespread lung involvement with numerous, moderately sized lesions and emphysematous lung regions. Imaging of this patient demonstrated more extensive respiratory disease than has previously been reported in BML, and rendered surgical resection of the nodules impossible. We describe the patient’s treatment with chemical castration and report some improvement in both lung imaging and function.

  • gynaecological cancer
  • lung function

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  • Contributors AA and DE were directly involved in patient care on multiple admissions and follow up clinics. All three authors agreed the case deserved publication and DE discussed this with the patient. AA collected spirometry data while DE and RS chose radiological images. RS and AA collaborated to summarise the patient notes and write the outline of the case and DE reviewed this and checked it matched with her understanding of the patient journey as lead consultant. DE outlined the available treatment strategies in this case and RS reviewed previous case reports and publications to check if any others had been mentioned. RS then drafted the discussion based on conversations with AA and DE, and then this was reviewed by all three authors. The final article was then reviewed by all three authors.

  • Funding The authors have not declared a specific grant for this research from any funding agency in the public, commercial or not-for-profit sectors.

  • Competing interests None declared.

  • Provenance and peer review Not commissioned; externally peer reviewed.

  • Patient consent for publication Obtained.

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