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Primary angiosarcoma of the breast: a radiation oncologist’s perspective with a concise review of the literature
  1. Rajpal Singh,
  2. Kundan Singh Chufal,
  3. Anjali K Pahuja,
  4. Tamilarasu Suresh,
  5. Rahul Lal Chowdhary and
  6. Irfan Ahmad
  1. Radiation Oncology, Rajiv Gandhi Cancer Institute and Research Centre, New Delhi, Delhi, India
  1. Correspondence to Dr Kundan Singh Chufal, kundan25{at}


A 28-year-old premenopausal woman presented with a painful rapidly growing mass in her right breast and was evaluated with a core needle biopsy, which was suggestive of poorly differentiated carcinoma. Immunohistochemical evaluation revealed primary angiosarcoma of breast. Whole body 18flouro-deoxyglucose positron emission tomography CT showed few metabolically active soft tissue lesions in upper inner quadrant of right breast. The patient underwent breast conservation surgery and in view of positive surgical margins, received adjuvant radiation therapy. Post-treatment completion, the patient has been disease free for 6 months. Primary angiosarcoma of the breast is a rare malignancy which is best managed with a surgery as first approach, with due importance being given to the patient’s perspective on their disease and choices for adjuvant treatment. Decisions in addition to adjuvant radiotherapy need to be made in the multidisciplinary clinic, due to paucity of data.

  • radiotherapy
  • breast cancer
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  • Contributors RS is responsible for drafting the manuscript and revising it. KSC participated in article formulation, editing and oversight. He is the guarantor. AKP participated in article formulation, editing and oversight. TS is responsible for generating the radiation treatment plan, performing quality assurance of delivered plan and also participated in article editing. RLC participated in article editing and data collection. IA is responsible for revising and editing the manuscript.

  • Funding The authors have not declared a specific grant for this research from any funding agency in the public, commercial or not-for-profit sectors.

  • Competing interests None declared.

  • Provenance and peer review Not commissioned; externally peer reviewed.

  • Patient consent for publication Obtained.

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