Parvovirus infection is usually asymptomatic especially in immunocompetent adults. When symptomatic it can range from mild to life threatening depending on the patient’s age and comorbidities. We report a case of a 40-year-old male patient with parvovirus infection who presented a purpuric rash in distal extremities, acute kidney injury, type II mixed cryoglobulinaemia and hypocomplementaemia. His renal biopsy showed a mesangioproliferative glomerulonephritis with positive immunoreactivity to C3, IgM and C1q. Parvovirus B19 was detected in the biopsy tissue by PCR. He was treated with prednisolone with total remission after 1 month. We discuss the diagnosis of kidney lesion due to parvovirus in an immunocompetent person, which is a very rare condition and its association with the cryoglobulinaemia diagnosis.
- acute renal failure
- renal intervention
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FSM and DM contributed equally.
Contributors FSM was responsible for writing the article, approving the final version and ensuring its integrity. DM was also responsible for writing the article, following the patient and approving the final version. VS was responsible for designing the article, transmitting the biopsy results, interpreting them for the article and approving its final version. CN was responsible for creating the article, revising it for critical intellectual content as well as detecting the parvovirus through PCR and interpreting the results. RG was responsible for critically revising the article, following the patient, approving the final version and ensuring that it was accurate. RA was responsible for designing the article, collecting and interpreting data and approving the final version.
Funding The authors have not declared a specific grant for this research from any funding agency in the public, commercial or not-for-profit sectors.
Competing interests None declared.
Provenance and peer review Not commissioned; externally peer reviewed.
Patient consent for publication Obtained.
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