You are here

Article Text

Article menu
Download PDFPDF
Reminder of important clinical lesson
CASE REPORT
Transient splenial lesion due to non-cirrhotic hyperammonaemia in dengue fever
  1. Robin George Manappallil1,
  2. Sunil V Nair2,
  3. Aryashree Kakkattil1 and
  4. Blessy Josphine1
  1. 1 Department of Internal Medicine, Baby Memorial Hospital, Calicut, Kerala, India
  2. 2 Department of Radio Diagnosis and Imaging, Baby Memorial Hospital, Calicut, Kerala, India
  1. Correspondence to Dr Robin George Manappallil, drrobingeorgempl{at}gmail.com

Abstract

Transient splenial lesion(TSL) is seen in a variety of conditions and is detectable only on MRI of the brain. Dengue fever (DF) is a common viral infection encountered in the tropics. The affected patients may face neurological complications like encephalopathy and intracranial haemorrhage, or even ischaemic stroke. Non-cirrhotic hyperammonaemia is a rare scenario; and its occurrence in DF is unknown. The patient being described had DF and developed dysarthria. His MRI brain showed splenial hyperintensity. Further evaluation revealed non-cirrhotic hyperammonaemia. To the best of our knowledge, TSL due to non-cirrhotic hyperammonaemia in DF is an unreported scenario.

  • Dengue fever
  • hyperammonemia
  • transient spenial lesion

https://doi.org/10.1136/bcr-2019-229407

Statistics from Altmetric.com

    Request Permissions

    If you wish to reuse any or all of this article please use the link below which will take you to the Copyright Clearance Center’s RightsLink service. You will be able to get a quick price and instant permission to reuse the content in many different ways.

    View Full Text

    Footnotes

    • Contributors RGM: concept and design, manuscript preparation, revision of manuscript and treating physician. SVN: critical revision of manuscript and radiologist. AK: resident in-charge. BJ: resident in-charge.

    • Funding The authors have not declared a specific grant for this research from any funding agency in the public, commercial or not-for-profit sectors.

    • Competing interests None declared.

    • Provenance and peer review Not commissioned; externally peer reviewed.

    • Patient consent for publication Obtained.