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CASE REPORT
Mitral and tricuspid valve repair in hypereosinophilic syndrome
  1. Ahmed M Al-Kaisey1,
  2. Zaal Meher-Homji1,
  3. Philip Hayward2 and
  4. Elizabeth Jones1
  1. 1 Cardiology, Austin Health, Melbourne, Victoria, Australia
  2. 2 Cardiac Surgery, Austin Health, Heidelberg, Victoria, Australia
  1. Correspondence to Dr Ahmed M Al-Kaisey, ahmed.alkaisey{at}gmail.com

Abstract

Hypereosinophilic syndrome (HES) is a rare systemic condition, defined as a persistently elevated eosinophil count associated with end organ damage and the absence of a primary cause. Cardiac involvement occurs in about 50% of patients with HES. Myocardial infiltration results in endomyocardial fibrosis, valve dysfunction and mural thrombus. The atrioventricular valves are almost always involved, resulting in regurgitation due to leaflet restriction, most commonly affecting the posterior mitral valve leaflet. Surgical management remains challenging in patients with HES with limited data on the choice of valve surgery. We describe the case of a 17-year-old woman with HES complicated by congestive cardiac failure secondary to severe mitral and tricuspid regurgitation. Because of refractory heart failure despite medical therapy, surgical mitral and tricuspid valve repair was performed, and an excellent 24-month outcome was achieved. We believe this is the first report of double valve repair in this rare condition.

  • heart failure
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Footnotes

  • Contributors AMA-K contributed to the collection of the history and data for this case report, consent of the patient, writing up the case report and literature review. ZM-H contributed to literature search, case report writing and figures design. PH was the operating surgeon in our case report and contributed to case report writing, revision of manuscript and literature review. EJ was the treating cardiologist in our case report and contributed to case report writing, revision of manuscript and literature review.

  • Funding The authors have not declared a specific grant for this research from any funding agency in the public, commercial or not-for-profit sectors.

  • Competing interests None declared.

  • Provenance and peer review Not commissioned; externally peer reviewed.

  • Patient consent for publication Obtained.

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