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Administration of a long-acting antipsychotic injection to a child while managing contraindicated polypharmacy interactions and transition between services
  1. Gazala Akram1 and
  2. Fiona Mitchell2
  1. 1 Strathclyde Institute of Pharmacy and Biomedical Sciences, University of Strathclyde, Glasgow, UK
  2. 2 NHS Greater Glasgow and Clyde, Glasgow, UK
  1. Correspondence to Dr Gazala Akram, gazala.akram{at}


Second-generation antipsychotics are used to treat a variety of psychiatric symptoms and illnesses as well as the behavioural aspects of various neurodevelopmental disorders. However, there is reluctance in using second-generation long-acting injectable antipsychotics in child psychiatry services. We present a case of a 12-year-old child whose presentation and medication regime warranted the use of aripiprazole long-acting injection against a backdrop of potential CYP P450 enzyme interactions as a consequence of polypharmacy. The case also describes the difficulties encountered working across different health sectors and agencies and highlights the ongoing need for skills-based Continuous Professional Development for Child and Adolescent Mental Health Services-based nursing staff.

  • Psychiatry (drugs and medicines)
  • Child and adolescent psychiatry (paediatrics)
  • Pharmacology and therapeutics

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  • Contributors Both authors contributed to the writing of this report. (S Hukin contributed with details that were requested during the review process).

  • Funding The authors have not declared a specific grant for this research from any funding agency in the public, commercial or not-for-profit sectors.

  • Competing interests None declared.

  • Provenance and peer review Not commissioned; externally peer reviewed.

  • Patient consent for publication Parental/guardian consent obtained.