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Thyroid-like low-grade papillary adenocarcinoma of nasopharynx
  1. Ainaz Sourati1,
  2. Mona Malekzadeh2 and
  3. Azadeh Rakhshan3
  1. 1 Radiation Oncology of Imam Hossein Hospital, Shahid Beheshti University of Medical Sciences, Tehran, Iran
  2. 2 Department of Radiation-Oncology, Shohada-e Tajrish Hospital, Tehran, Iran
  3. 3 Department of Pathology, Shohada-e Tajrish Hospital, Tehran, Iran
  1. Correspondence to Dr Mona Malekzadeh, Ainazsouraty{at}


We report a 35-year-old woman with complaints of nasal obstruction and mild post-nasal drip for 6 months. She did not improve with medical treatment. Clinical examination had no positive finding. She was evaluated with a CT scan and MRI that revealed a polypoid mass lesion in nasopharynx without any adhesion to adjacent tissue. Endoscopic examination of nasopharynx revealed an exophytic nasopharyngeal mass in anterior wall of nasopharynx that complete macroscopic transnasal endoscopic resection was performed. The histopathological examination reported thyroid-like low-grade nasopharyngeal papillary adenocarcinoma that was confirmed on immunohistochemical staining. After complete macroscopic resection of the mass, patient was regularly followed-up for 6 years and there was no evidence of recurrence. This example has the educational tips of the optimal therapeutic strategies for primary nasopharyngeal adenocarcinomas with long follow-up.

  • head and neck cancer
  • radiotherapy
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  • Contributors All authors, MM, AS and AR have participated sufficiently in this work and each author certifies that this material has not been submitted to or published in any other publication.

  • Funding The authors have not declared a specific grant for this research from any funding agency in the public, commercial or not-for-profit sectors.

  • Competing interests None declared.

  • Provenance and peer review Not commissioned; externally peer reviewed.

  • Patient consent for publication Obtained.

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